A new white paper from the World Economic Forum, The Economic Rationale for a Global Commitment to Invest in Oral Health, addresses the negative impact of poor oral health across the globe and proposes innovative policy, investment and delivery solutions. This paper, written in partnership with the American Dental Association, Colgate-Palmolive Company, and Henry Schein, outlines the economic rationale for investing in oral health and presents concrete action pathways for public, private and civil society leaders for addressing the global epidemic of oral disease.